2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-118338
    WRR-483
    		Inhibitor
    WRR-483 is an analog of K11777, an inhibitor of cruzain, used to inhibit the proliferation of Trypanosoma cruzi in cell culture. WRR-483 can eradicate parasitic infection in an acute Chagas disease mouse model. WRR-483 is an irreversible cysteine protease inhibitor that shows pH-dependent high affinity and potent trypanocidal activity against cruzain and T. cruzi infection, and is expected to inhibit Chagas disease.
    WRR-483
  • HY-W743773
    γ-Cyhalothrin
    		Inhibitor
    γ-Cyhalothrin is an orally active, blood-brain barrier permeable Type II synthetic pyrethroid insecticide. γ-Cyhalothrin is the insecticidally active enantiomer of λ-Cyhalothrin (HY-B0836). γ-Cyhalothrin disrupts voltage-gated sodium channels, induces salivation and reduces spontaneous activity in rats. γ-Cyhalothrin exerts toxic effects on aquatic invertebrates and fish, triggers community-level effects in aquatic ecosystems, and inhibits host-seeking Ixodes scapularis nymphs in residential lawn ecotones. γ-Cyhalothrin is applicable to insecticidal-related research.
    γ-Cyhalothrin
  • HY-Y0055R
    Phenothiazine (Standard)
    Phenothiazine (Standard) is the analytical standard of Phenothiazine. This product is intended for research and analytical applications. Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases.
    Phenothiazine (Standard)
  • HY-114909
    TachypleginA
    		Inhibitor
    TachypleginA can inhibit the motility of T. gondii by binding directly and covalently to C58 of TgMLC1，thereby causing a decrease in the activity of the parasite's myosin motor.
    TachypleginA
  • HY-178326
    NEU-5123
    		Inhibitor
    NEU-5123 is a human kinase inhibitor with potent inhibitory activity to several kinases. NEU-5123 is a Trypanosome proliferation inhibitor. NEU-5123 can be used for the research of infection.
    NEU-5123
  • HY-B0175R
    Toltrazuril (Standard)
    		Inhibitor
    Toltrazuril (Standard) is the analytical standard of Toltrazuril. This product is intended for research and analytical applications. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.
    Toltrazuril (Standard)
  • HY-164004
    Stevaladil
    		Inhibitor
    Stevaladil, an vasodilator, is a amebicide agent.
    Stevaladil
  • HY-175648
    Antiparasitic agent-28
    		Inhibitor
    Antiparasitic agent-28 is an orally active, selective inhibitor of Toxoplasma gondii phenylalanine tRNA synthetase (TgcPheRS) with blood-brain barrier penetration. Antiparasitic agent-28 inhibits the growth of T. gondii tachyzoites (TgME49-Fluc strain) an (EC50 = 1 nM) and T. gondii bradyzoites (Tg68nLuc strain) induced by alkaline (EC50 = 3 nM) and glutamine-rich medium (EC50 = 0.1 nM). Antiparasitic agent-28 demonstrates potent anti-toxoplasmosis efficacy in mice infected with TgME49-Fluc tachyzoites. Antiparasitic agent-28 can be used for the study of Toxoplasma gondii infection.
    Antiparasitic agent-28
  • HY-N12178
    16-Deethylindanomycin
    		Inhibitor
    16-Deethylindanomycin (A 83094A) is an antibiotic, which can be produced by Streptomyces setonii. 16-Deethylindanomycin exhibits antimicrobial activities against gram-positive bacteria Staphylococcus spp. and Streptococcus with MIC of 2-4 µg/mL. 16-Deethylindanomycin exhibits anticoccidial activity against Eimeria tenella.
    16-Deethylindanomycin
  • HY-17656
    C3361
    		Inhibitor
    C3361 is a moderate specific Plasmodium falciparum hexose transporter 1 (PfHT1) and Plasmodium berghei hexose transporter 1 (PbHT1) inhibitor with Ki values of 8.6 and 9.4 μM. C3361 inhibits TgGT1 with a Ki of 82 μM. C3361 attenuates hepatic (IC50 = 15 μM) and ookinete development of P. berghei. C3361 can suppress the growth of blood-stage parasites. C3361 can be used for the research of infection, such as malaria.
    C3361
  • HY-137801
    Sesquicillin A
    		Inhibitor
    Sesquicillin A is an insecticidal antibiotic, a fungal metabolite isolated from white plantain. Sesquicillin A inhibits the growth of A. salina brine shrimp with the MIC value of 6.25 µg/mL.
    Sesquicillin A
  • HY-175507
    TRPMPZQ-IN-1
    		Inhibitor
    TRPMPZQ-IN-1 (Compound 52) is a TRPMPZQ inhibitor, with an EC50 of 0.38 μM against TRPMPZQ from Spirometra erinaceieuropaei. TRPMPZQ-IN-1 exhibits antiparasitic activity, showing an EC50 of 4.3 μM against Echinococcus multilocularis. TRPMPZQ-IN-1 can be used in antiparasitic research.
    TRPMPZQ-IN-1
  • HY-17008R
    Toltrazuril sulfone (Standard)
    		Inhibitor
    Toltrazuril (sulfone) (Standard) is the analytical standard of Toltrazuril (sulfone). This product is intended for research and analytical applications. Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry.
    Toltrazuril sulfone (Standard)
  • HY-138812
    Antileishmanial agent-28
    		Inhibitor
    Antileishmanial agent-28 (Compd 12) is an antileishmanial agent, with EC50 values of 1.5 μM (L.donovani), 13 μM (L.amazonensis) and 18 μM (J774A.1), respectively.
    Antileishmanial agent-28
  • HY-178040
    Insecticidal agent 26
    		Inhibitor
    Insecticidal agent 26 (Compound A11), a spiro insecticidal agent, is a dual-functional inhibitor of pest Acetyl-CoA carboxylase (ACC) and Pyruvate carboxylase (PC). Insecticidal agent 26 has potent insecticidal activity against Sogatella furcifera with a LC50 of 11.0  μg/mL, with significant biosafety to bees. Insecticidal agent 26 can be used for management of white-backed planthoppers (WBPs).
    Insecticidal agent 26
  • HY-179116
    BL-1005
    		Inhibitor
    BL-1005 (BS2463), thiophen-2-yl pyrimidine (TTP), is a potent paralytic of Schistosoma mansoni with an EC50 of 37 nM. BL-1005 shows low cytotoxicity for HEK293, HeLa and HepG2 cell with CC50 >20 μM. BL-1005 can induce paralysis in both adult and juvenile S. mansoni. BL-1005 can be used for the research of infection.
    BL-1005
  • HY-B1322AR
    Amodiaquine (Standard)
    		Inhibitor
    Amodiaquine (Standard) is the analytical standard of Amodiaquine. This product is intended for research and analytical applications. Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
    Amodiaquine (Standard)
  • HY-W719544
    Cyenopyrafen
    		Inhibitor
    Cyenopyrafen is a mitochondrial complex II inhibitor and acaricide. Cyenopyrafen controls spider mites on fruit trees, vegetables and flowers.
    Cyenopyrafen
  • HY-B0529AR
    Azlocillin sodium salt (Standard)
    Azlocillin (sodium salt) (Standard) is the analytical standard of Azlocillin (sodium salt). This product is intended for research and analytical applications. Azlocillin sodium salt (Sodium azlocillin), a semisynthetic penicillin, is a broad spectrum β-lactam antibiotic. Azlocillin sodium salt shows antipseudomonal activity, and also potent against the malarial parasite Plasmodium falciparum.
    Azlocillin sodium salt (Standard)
  • HY-159900
    Antimalarial agent 46
    		Inhibitor
    Antimalarial agent 46 (Compound 42a) is an antimalarial agent with antimalarial activity. Antimalarial agent 46 shows inhibitory activity against P. falciparum lines.
    Antimalarial agent 46
Parasite Isoform Comparison

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